Glutathione-related antioxidant defense system in patients with hypertensive retinopathy
نویسندگان
چکیده
منابع مشابه
Role of glutathione metabolism and glutathione-related antioxidant defense systems in hypertension.
The risk of developing chronic hypertension increases with age. Among others factors, increased oxidative stress is a well-recognized etiological factor for the development of hypertension. The co-occurrence of oxidative stress and hypertension may occur as a consequence of a decrease in antioxidant defense system activity or elevated reactive oxygen species generation. Glutathione is a major i...
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BACKGROUND The association between hypertension and diabetes has been linked to increased oxidative stress with age. This study was to examine the level of age-dependent alterations in antioxidant defense system between patients having hypertension and/or type-2 diabetes. METHODS The study was conducted at the Ahmadu Bello University Teaching Hospital, Zaria-Nigeria, using 200 Subjects recrui...
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Introduction: Hypertension is one of the most common chronic diseases in the world today. Various studies have shown that people with hypertension have a lower life quality than people with normal blood pressure. Despite various studies on hypertension, little information is available on the life quality in patients with hypertension. Due to the relative ambiguity in this regard, the study has ...
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PURPOSE Increase in reactive oxygen species (ROS) is one of the major retinal metabolic abnormalities associated with the development of diabetic retinopathy. NF-E2-related factor 2 (Nrf2), a redox sensitive factor, provides cellular defenses against the cytotoxic ROS. In stress conditions, Nrf2 dissociates from its cytosolic inhibitor, Kelch like-ECH-associated protein 1 (Keap1), and moves to ...
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ژورنال
عنوان ژورنال: romanian journal of ophthalmology
سال: 2021
ISSN: 2457-4325,2501-2533
DOI: 10.22336/rjo.2021.9